A drive and guide mechanism for a flap such as a landing flap arranged in an aircraft wing, especially in the trailing edge of the wing includes a carriage to which the flap is pivoted. The carriage is movable along a support and guide rail. A drive arm and control system is operated by a drive mechanism (8) with a drive lever (9) which connects a drive rod (10) to the carriage. The kinematic drive mechanism (8) includes a control link (5), a two armed lever or control link (6), a control rod (7), and the drive rod (10). The two armed control link (6) is journalled to the carriage (4) in a tiltable manner. One arm of the two armed link (6) and the control link (5) connect the carriage with the flap (2). The one arm (6a) and the control link (5) form a four bar link with a section of the carriage and a section of the flap. The second arm (6b) of the control link (6) is connected with the drive lever (9) through a drive rod (10). The pivot point (7a) of the control rod (7) is angularly displaced relative to the pivot point (10a) of the drive rod (10). The first mentioned pivot point (7a) further has a spacing (9a) from the rotational axis (A) of the drive mechanism (8) which differs from a respective spacing (9b) of the pivot point (10a) of the drive rod (10).