Four color toners of yellow, magenta, cyan and black, and four two-component developers containing the four color toners respectively in combination with a resin-coated ferrite carrier suitable for multi-color electrophotographic copying are provided Each of the four-color toners is strictly regulated in relation not only to the carrier but also to the other color toners. More specifically, each color toner is strictly controlled with respect to a particle size distribution, freeness from agglomeration, melting characteristics including heat-absorption peaks and apparent viscosity on melting, chromaticity, triboelectric chargeability and optical toner concentration detection characteristic. Because of the strict regulation of these various parameters, the resultant multi-color toner or developer system shows excellent performances at every stage of multi-color electrophotography including development, transfer and fixing (color-mixing) for a long period of successive copying.