发明授权
- 专利标题： Method for selective reduction of Lp(a)
- 专利标题（中）： 选择性还原Lp（a）
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申请号： US844903申请日： 1992-03-02
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公开(公告)号： US5272166A公开(公告)日： 1993-12-21
- 发明人: Jan L. Breslow , Dov Gavish
- 申请人： Jan L. Breslow , Dov Gavish
- 申请人地址： NY New York
- 专利权人： The Rockefeller University
- 当前专利权人： The Rockefeller University
- 当前专利权人地址： NY New York
- 主分类号： A61K31/095
- IPC分类号： A61K31/095 ; A61K31/185 ; A61K31/19 ; A61K31/195 ; A61K31/415 ; A61K38/06
摘要：
The present invention relates to methods and corresponding agents for lowering plasma Lp(a) levels by the administration of agents that reduce Lp(a) and selectively separate therefrom the apo(a) component and/or prevent Lp(a) formation. Suitable agents include sulfhydryl reducers, such as N-acetylcysteine. The present method and agents may be administered alone or in conjunction with other therapy for the lowering of LDL cholesterol.
公开/授权文献
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