发明授权
- 专利标题： N-substituted heterocyclic derivatives useful in the treatment of cardiovascular disorders
- 专利标题（中）： 可用于治疗心血管疾病的N-取代的杂环衍生物
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申请号： US901145申请日： 1992-06-19
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公开(公告)号： US5274104A公开(公告)日： 1993-12-28
- 发明人: Joelle Arnaud , Jean-Louis Assens , Claude Bernhart , Bernard Ferrari , Frederique Haudricourt , Pierre Perreaut
- 申请人： Joelle Arnaud , Jean-Louis Assens , Claude Bernhart , Bernard Ferrari , Frederique Haudricourt , Pierre Perreaut
- 申请人地址： FRX Paris
- 专利权人： Elf Sanofi, A French Corp.
- 当前专利权人： Elf Sanofi, A French Corp.
- 当前专利权人地址： FRX Paris
- 优先权： FRX9107685 19910621
- 主分类号： A61K31/415
- IPC分类号： A61K31/415 ; A61K31/4184 ; A61K31/496 ; A61K31/505 ; A61P9/00 ; A61P9/12 ; A61P27/02 ; A61P43/00 ; C07D233/70 ; C07D233/84 ; C07D235/02 ; C07D239/36 ; C07D239/40 ; C07D403/10 ; C07D403/12 ; C07D413/12 ; C07D417/12 ; C12N9/99 ; A61K31/42 ; C07D233/54 ; C07D257/04 ; C07D271/06 ; C07D271/08
摘要：
The present invention relates to N-substituted heterocyclic derivatives of formula: ##STR1## processes for their preparation, and pharmaceutical compositions which contain them. The compounds according to the invention are non-peptide compounds which oppose the action of angiotensin II. The compounds according to the invention are thus useful in the treatment of cardiovascular disorders such as hypertension and heart failure.
公开/授权文献
- US6068594A Parameter disturbance response apparatus 公开/授权日：2000-05-30
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