发明授权
US5288887A Diamine platinum(IV) complexes having mixed carboxylate ligands as
antitumor agents
失效
将具有混合的羧酸盐配体的铂（IV）配合物二胺作为抗肿瘤剂
- 专利标题： Diamine platinum(IV) complexes having mixed carboxylate ligands as antitumor agents
- 专利标题（中）： 将具有混合的羧酸盐配体的铂（IV）配合物二胺作为抗肿瘤剂
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申请号： US978788申请日： 1992-11-19
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公开(公告)号： US5288887A公开(公告)日： 1994-02-22
- 发明人: Abdul R. Khokhar , Zahid H. Siddik , Salaam Al-Baker
- 申请人： Abdul R. Khokhar , Zahid H. Siddik , Salaam Al-Baker
- 申请人地址： TX Austin
- 专利权人： Board of Regents, The University Texas System
- 当前专利权人： Board of Regents, The University Texas System
- 当前专利权人地址： TX Austin
- 主分类号： C07F15/00
- IPC分类号： C07F15/00 ; A61K31/28
摘要：
Platinum(IV) complexes with mixed carboxylato ligands having the formula: ##STR1## where X.sup.1 and X.sup.2 are carboxylato, or are jointly dicarboxylato, where .sup.1 Y and Y.sup.2 are carboxylato, and where Z is either diaminocyclohexane or ethylenediamine, have been found to have desirable antitumor activity, as well as relatively low levels of toxicity.
公开/授权文献
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