发明授权
US5288896A 3,5-di-t-butyl-4-hydroxylphenylmethylhydroxylamines and their
derivatives, pharmaceutical compositions, and methods of use therefor
失效
3,5-二叔丁基-4-羟基苯基甲基羟胺及其衍生物，药物组合物及其使用方法
- 专利标题： 3,5-di-t-butyl-4-hydroxylphenylmethylhydroxylamines and their derivatives, pharmaceutical compositions, and methods of use therefor
- 专利标题（中）： 3,5-二叔丁基-4-羟基苯基甲基羟胺及其衍生物，药物组合物及其使用方法
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申请号： US821103申请日： 1992-01-15
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公开(公告)号： US5288896A公开(公告)日： 1994-02-22
- 发明人: Thomas Capiris , David T. Connor , Jagadish C. Sircar
- 申请人： Thomas Capiris , David T. Connor , Jagadish C. Sircar
- 申请人地址： NJ Morris Plains
- 专利权人： Warner-Lambert Company
- 当前专利权人： Warner-Lambert Company
- 当前专利权人地址： NJ Morris Plains
- 主分类号： C07C239/12
- IPC分类号： C07C239/12 ; C07C259/06 ; C07C271/16 ; C07C275/64 ; C07C335/40 ; C07C271/00
摘要：
The present invention is a novel compound which is a 3,5-di-t-butyl-4-hydroxyphenylmethylhydroxylamine or derivative thereof and a pharmaceutically acceptable acid addition or base salt thereof, pharmaceutical composition and methods of use therefor. The invention compounds are now found to have activity as inhibitors of one or both of cyclooxygenase and 5-lipoxygenase providing treatment of conditions advantageously affected by such inhibition including inflammation, arthritis, pain, fever, and the like.
公开/授权文献
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