发明授权
- 专利标题: Xanthine derivatives
- 专利标题(中): 黄嘌呤衍生物
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申请号: US839690申请日: 1992-02-24
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公开(公告)号: US5290782A公开(公告)日: 1994-03-01
- 发明人: Fumio Suzuki , Junichi Shimada , Akio Ishii , Tetsuji Ohno , Akira Karasawa , Kazuhiro Kubo , Hiromi Nonaka
- 申请人: Fumio Suzuki , Junichi Shimada , Akio Ishii , Tetsuji Ohno , Akira Karasawa , Kazuhiro Kubo , Hiromi Nonaka
- 申请人地址: JPX Tokyo
- 专利权人: Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人: Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX1-226642 19890901; JPX3-029796 19910225
- 主分类号: C07D473/06
- IPC分类号: C07D473/06 ; C07D473/08 ; C07D473/20 ; C07D473/22 ; C07D473/02 ; A61K31/52
摘要:
Novel xanthine compounds represented by the following formula: ##STR1## wherein each of X.sup.1 and X.sup.2 independently represents oxygen or sulfur; and Q represents; ##STR2## where ----- represents a single bond or a double bond; Y represents a single bond or alkylene, n represents 0 or 1, each of W.sup.1 and W.sup.2 independently represents hydrogen, lower alkyl or amino, Z represents --CH.sub.2 -, --O--, --S-- or --NH--; represents ##STR3## each of R.sup.1 and R.sup.2 independently represents hydrogen, lower alkyl, allyl or propargyl; and R.sup.3 represents hydrogen or lower alkyl, and when Q represents the groups other than ##STR4## each of R.sup.1, R.sup.2 and R.sup.3 independently represents hydrogen or lower alkyl;provided that when Q is ##STR5## then R.sup.1 R.sup.2 and R.sup.3 are notsimultaneously methyl; and pharmaceutically acceptable salts thereof have a diuretic effect, a renal-protecting effect and a bronchodilatory effect.
公开/授权文献
- US5939205A Gas barrier resin film 公开/授权日:1999-08-17
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