发明授权
- 专利标题： Therapeutic agent for ischemic diseases
- 专利标题（中）： 缺血性疾病治疗剂
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申请号： US915877申请日： 1992-07-20
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公开(公告)号： US5290785A公开(公告)日： 1994-03-01
- 发明人: Masayuki Kato , Kiyotaka Ito , Hisashi Takasugi
- 申请人： Masayuki Kato , Kiyotaka Ito , Hisashi Takasugi
- 申请人地址： JPX Osaka
- 专利权人： Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人： Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人地址： JPX Osaka
- 优先权： GBX8822646 19880927; GBX8903044 19890210
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D221/06 ; A61K31/44
摘要：
The invention relates to a method of treating cardiac ischemic disease using a compound of the formula: ##STR1## wherein R.sup.1 is hydrogen, lower alkyl, lower alkenyl or N,N-di(lower)alkylaminomethyl,R.sup.2 is hydrogen, lower alkyl or halogen,R.sup.3 is imidazolyl or pyridyl, each of which may have substituent(s) selected from lower alkyl and imino-protective group, andR.sup.4 is hydrogen, lower alkyl, lower alkenyl or hydroxy(lower)alkyl and R.sup.5 is hydrogen, hydroxy or lower alkanoyloxy, orR.sup.4 and R.sup.5 are linked together to form an additional bond,or a pharmaceutically acceptable salt thereof.
公开/授权文献
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