发明授权
US5298396A Method for identifying T cells disease involved in autoimmune disease
失效
鉴定涉及自身免疫性疾病的T细胞疾病的方法
- 专利标题： Method for identifying T cells disease involved in autoimmune disease
- 专利标题（中）： 鉴定涉及自身免疫性疾病的T细胞疾病的方法
-
申请号： US732114申请日： 1991-07-18
-
公开(公告)号： US5298396A公开(公告)日： 1994-03-29
- 发明人: Brian L. Kotzin , Philippa Marrack , John Kappler , Xavier Paliard
- 申请人： Brian L. Kotzin , Philippa Marrack , John Kappler , Xavier Paliard
- 申请人地址： CO Denver
- 专利权人： National Jewish Center for Immunology and Respiratory Medicine
- 当前专利权人： National Jewish Center for Immunology and Respiratory Medicine
- 当前专利权人地址： CO Denver
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C12Q1/68 ; G01N33/50 ; G01N33/564 ; G01N33/569
摘要：
The invention relates to a method for identifying T cell populations involved in autoimmune diseases. This involves determining levels of a V.beta. element in a body fluid sample of a patient and comparing this to normal levels. Variation from normal levels is indicative of an autoimmune disease. The invention also involves assaying T cell subpopulations in a sample to determine clonality of .beta. chains. Clonality can also be used to diagnose autoimmune disorders.
公开/授权文献
信息查询
IPC分类:
