A dispensing device has a shell (11) which may be connected to a container (14) for a fluid to be dispensed, such as an injectable pharmaceutical compound. The device has a fixed first threaded member (21) and a second threaded member (22) surrounding the first member, the first and second members each having equi-spaced threaded segments (27 and 29) with non-threaded segments (28) therebetween whereby the second member will be wound axially when rotated about the first member but may be positioned for axial sliding movement with respect to the first member. A plunger (23) is slidably mounted within the first member (21) and has a portion (33) engageable with the threads of the second member. A dose setting sleeve (53) surrounds the second member and has threads (54) engaged with the device shell, the sleeve being coupled to the second member for rotation therewith. A dose is set by winding the second member (22) away from a fixed stop (25) until the sleeve (53) indicates the required does amount, whereafter the second member (22) is slid axially back to the fixed stop (25), the plunger (23) being thrust forwardly thereby to expel fluid from the container.