发明授权
US5308614A Methods for the production of antibodies and induction of immune
responses to tumor-associated gangliosides by immunization with
ganglioside lactones
失效
通过免疫神经节苷脂内酯产生抗体和诱导与肿瘤相关神经节苷脂的免疫反应的方法
- 专利标题: Methods for the production of antibodies and induction of immune responses to tumor-associated gangliosides by immunization with ganglioside lactones
- 专利标题(中): 通过免疫神经节苷脂内酯产生抗体和诱导与肿瘤相关神经节苷脂的免疫反应的方法
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申请号: US996509申请日: 1992-12-21
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公开(公告)号: US5308614A公开(公告)日: 1994-05-03
- 发明人: Sen-Itiroh Hakomori
- 申请人: Sen-Itiroh Hakomori
- 申请人地址: WA Seattle
- 专利权人: The Biomembrane Institute
- 当前专利权人: The Biomembrane Institute
- 当前专利权人地址: WA Seattle
- 主分类号: A61K31/70
- IPC分类号: A61K31/70 ; A61K39/00 ; C07K16/30 ; C12P21/08 ; A61K37/00
摘要:
The present invention relates to an improved method for the production of antibodies to tumor-associated gangliosides using ganglioside lactones. The resulting antibodies are useful in the detection and treatment of tumors containing gangliosides. The present invention also relates to methods of treatment of tumors by active immunization using ganglioside lactones.
公开/授权文献
- US5998660A Process for preparing carboxylic acids 公开/授权日:1999-12-07
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