发明授权
US5308839A Composition comprising non-steroidal anti-inflammatory agent tenidap and
effectively non-antibacterial tetracycline
失效
组合物包含非甾体抗炎剂tenidap和有效的非抗菌四环素
- 专利标题： Composition comprising non-steroidal anti-inflammatory agent tenidap and effectively non-antibacterial tetracycline
- 专利标题（中）： 组合物包含非甾体抗炎剂tenidap和有效的非抗菌四环素
-
申请号： US940540申请日： 1992-09-04
-
公开(公告)号： US5308839A公开(公告)日： 1994-05-03
- 发明人: Lorne M. Golub , Nangavarum S. Ramamurthy , Thomas F. McNamara , Robert A. Greenwald
- 申请人： Lorne M. Golub , Nangavarum S. Ramamurthy , Thomas F. McNamara , Robert A. Greenwald
- 申请人地址： NY Albany
- 专利权人： The Research Foundation of State University of New York
- 当前专利权人： The Research Foundation of State University of New York
- 当前专利权人地址： NY Albany
- 主分类号： A61K31/19
- IPC分类号： A61K31/19 ; A61K31/195 ; A61K31/40 ; A61K31/405 ; A61K31/54 ; A61K31/60 ; A61K31/65 ; A61K45/00 ; A61P29/00 ; A61P43/00
摘要：
A method for treating mammals suffering from rheumatoid arthritis, other tissue-destructive conditions, and chronic inflammatory or other conditions associated with excess metalloproteinase activity comprising administering to the mammal an amount of a tetracycline that is effectively anti-metalloproteinase, but that is not effectively antimicrobial, and an amount of a non-steroidal anti-inflammatory agent which, when combined with the effectively anti-metalloproteinase amount of tetracycline, results in a significant reduction of tissue destruction and/or bone loss.
公开/授权文献
信息查询
