发明授权
- 专利标题: Substituted aromatic sulfonamides as antiglaucoma agents
- 专利标题(中): 取代的芳族磺酰胺作为抗青光眼剂
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申请号: US899413申请日: 1992-06-16
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公开(公告)号: US5308863A公开(公告)日: 1994-05-03
- 发明人: John J. Baldwin , Gerald S. Ponticello , Charles N. Habecker , Harold G. Selnick
- 申请人: John J. Baldwin , Gerald S. Ponticello , Charles N. Habecker , Harold G. Selnick
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: A61K31/38
- IPC分类号: A61K31/38 ; A61K31/435 ; A61P17/00 ; A61P27/02 ; A61P27/06 ; C07D495/04 ; C07D495/20 ; C07D333/00
摘要:
Thieno[2,3-b]thiopyran-2-sulfonamides and ring homologs with a hydrophilic substituted-alkyl group adjacent to the thiopyran sulfur are carbonic anhydrase inhibitors topically effective in lowering intraocular pressure.