发明授权
US5310735A Carbapenem derivatives having antibiotic activity, their preparation and
their use
失效
具有抗生素活性的碳青霉烯类衍生物及其制备及其应用
- 专利标题: Carbapenem derivatives having antibiotic activity, their preparation and their use
- 专利标题(中): 具有抗生素活性的碳青霉烯类衍生物及其制备及其应用
-
申请号: US938483申请日: 1992-08-31
-
公开(公告)号: US5310735A公开(公告)日: 1994-05-10
- 发明人: Isao Kawamoto , Masao Miyauchi , Eiji Nakayama , Rokuro Endo , Satoshi Ohya , Yukio Utsui
- 申请人: Isao Kawamoto , Masao Miyauchi , Eiji Nakayama , Rokuro Endo , Satoshi Ohya , Yukio Utsui
- 申请人地址: JPX Tokyo
- 专利权人: Sankyo Company, Limited
- 当前专利权人: Sankyo Company, Limited
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX2-42796 19900223; JPX2-212283 19900810
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; A61K31/40 ; A61K31/435 ; A61K31/44 ; A61K31/495 ; A61K31/55 ; C07D477/00 ; C07D477/10 ; C07D477/12 ; C07D477/20 ; A01N43/00 ; A61K31/395
摘要:
Carbapenem compounds of formula (I): ##STR1## in which: A is a fully saturated heterocyclic group, of which at least one ring atom is nitrogen; R.sup.1 is hydrogen or methyl; R.sup.2 is hydrogen or alkyl; R.sup.3 is hydrogen or a negative ion; Q is: (i) --B--N.sup.+ R.sup.8 R.sup.9 R.sup.10, where R.sup.8, R.sup.9 and R.sup.10 are alkenyl, alkynyl or optionally substituted alkyl, and B is alkylene or alkylidene.
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