发明授权
- 专利标题: Imidazoles for the treatment of atherosclerosis
- 专利标题(中): 咪唑用于治疗动脉粥样硬化
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申请号: US881034申请日: 1992-05-11
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公开(公告)号: US5310748A公开(公告)日: 1994-05-10
- 发明人: Richard G. Wilde , C. Anne Higley , Jeffrey T. Billheimer , Ruth R. Wexler
- 申请人: Richard G. Wilde , C. Anne Higley , Jeffrey T. Billheimer , Ruth R. Wexler
- 申请人地址: DE Wilmington
- 专利权人: The Du Pont Merck Pharmaceutical Company
- 当前专利权人: The Du Pont Merck Pharmaceutical Company
- 当前专利权人地址: DE Wilmington
- 主分类号: C07D233/84
- IPC分类号: C07D233/84 ; C07D401/12 ; C07D403/12 ; A61K31/415
摘要:
Disclosed are imidazoles as inhibitors of acylCoA:cholesterol acyltransferase (ACAT), processes for their preparation, pharmaceutical compositions, and their use as antihypercholesterolemics and/or antiatherosclerotics.