发明授权
- 专利标题: Azabicyclo oxime and amine cholinergic agents and methods of treatment
- 专利标题(中): 氮杂双环肟和胺胆碱剂及其治疗方法
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申请号: US830申请日: 1993-01-05
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公开(公告)号: US5318978A公开(公告)日: 1994-06-07
- 发明人: David J. Lauffer , Haile Tecle
- 申请人: David J. Lauffer , Haile Tecle
- 申请人地址: NJ Morris Plains
- 专利权人: Warner-Lambert Company
- 当前专利权人: Warner-Lambert Company
- 当前专利权人地址: NJ Morris Plains
- 主分类号: C07D471/08
- IPC分类号: C07D471/08 ; C07D498/08 ; A61K31/435
摘要:
Pharmaceutically useful nitrogen containing cyclic oxime and amine substituted compounds of the formulas I to XVI are disclosed (See specification for definitions of the substituents). Specifically, the compounds are 1-azabicyclo [3.2.1] oximes, 1-azabicyclo [3.3.1] oximes, 1-aza-4-oxobicyclo [3.3.1] oximes, 1-aza-4-oxobicyclo [3.2.1] oximes, and the corresponding amines wherein the heterocyclic ring contains 7 or 8 carbon atoms ##STR1##
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