发明授权
- 专利标题： Derivatives and anologs of monoethylglycinexylidide
- 专利标题（中）： 单乙基甘氨酸的衍生物和阴离子
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申请号： US820727申请日： 1992-01-14
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公开(公告)号： US5319105A公开(公告)日： 1994-06-07
- 发明人: Lawrence Kolaczkowski , Mark Littlefield
- 申请人： Lawrence Kolaczkowski , Mark Littlefield
- 申请人地址： IL Abbott Park
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： IL Abbott Park
- 主分类号： G01N33/52
- IPC分类号： G01N33/52 ; A61K49/00 ; C07D227/00 ; C07D493/10 ; C07K14/435 ; C07K14/76 ; C07K14/765 ; C09B11/08 ; C09B11/28 ; C09B29/12 ; G01N33/53
摘要：
A substituted monoethylglycinexylidide or analogue is disclosed. The xylidide or analogue has the structure of FIG. 1 of the attached drawings where M is CH.sub.2 NHCH.sub.2 CH.sub.3, CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3 or CH.sub.2 OCH.sub.2 CH.sub.3, one of Y.sup.1 and Y.sup.2 is H and the other is a protein or a fluorescein moiety chemically bonded to the glycinexylidide or analogue moiety. Also disclosed is a method for carrying out immunoassays for MEGX, which has the structure of FIG. 3 of the attached drawings. The method for carrying out immunoassays involves using the foregoing compounds as tracers and immunogens.
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