A label holder made from a single piece of molded plastic with an area of reduced thickness (i.e., a living hinge) dividing the single piece into a back panel and a transparent front panel. The back panel has an area into which a label is placed. By applying finger pressure to the front panel, the holder can be closed along the living hinge until the front and back panels contact each other. Each locking tab on a panel interlocks with a corresponding free edge on the other panel and locking the label in a sandwiched condition. A release lip on the front panel facilitates unlocking and opening of the holder by similar finger pressure. The back panel has attachment means allowing easy insertion into any surface adapted with appropriate receiving means. Once connected, the holder is securely attached to the surface, while at the same time being easily removeable for quick and simple replacement.