发明授权
- 专利标题: Composition and method for treating cancer
- 专利标题(中): 用于治疗癌症的组合物和方法
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申请号: US972935申请日: 1992-11-06
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公开(公告)号: US5360803A公开(公告)日: 1994-11-01
- 发明人: Tadao Shishido , Lan B. Chen
- 申请人: Tadao Shishido , Lan B. Chen
- 申请人地址: MA Boston JPX Kanagawa
- 专利权人: Dan Farber Cancer Institute,Fuji Photo Film Co., Ltd.
- 当前专利权人: Dan Farber Cancer Institute,Fuji Photo Film Co., Ltd.
- 当前专利权人地址: MA Boston JPX Kanagawa
- 主分类号: A61K31/41
- IPC分类号: A61K31/41 ; A61K31/415 ; A61K31/42 ; A61K31/425 ; A61K31/426 ; A61K31/428 ; A61K31/44 ; A61K31/4427 ; A61K31/47 ; A61K31/495 ; A61K31/50 ; A61K31/505 ; A61K31/555 ; A61P35/00 ; C07D277/20 ; C07D277/34 ; C07D277/66 ; C07D277/84 ; C07D401/14 ; C07D413/14 ; C07D417/04 ; C07D417/14 ; C07D421/14 ; C07D471/04 ; C07D513/04
摘要:
A pharmaceutical composition for treatment of cancer comprises:(A) a therapeutically effective amount of at least one compound selected from the group consisting of compounds represented by the General Formula (I) ##STR1## wherein X.sub.1 and X.sub.2, which may be the same or different, each represents O, S, Se, --CH.dbd.CH--, ##STR2## Y.sub.1 represents O, S, Se, or ##STR3## R.sub.1 and R.sub.3, which may be the same or different, each represents an alkyl group;R.sub.2 represents an alkyl group, an aryl group or a heterocyclic group;Z.sub.1 and Z.sub.2, which may be the same or different, each represents an atomic group necessary to form a 5- or 6-membered ring;L.sub.1 represents a methine group or L.sub.1 and R.sub.3 may combine and form a 5- or 6-membered ring;R.sub.4 and R.sub.5, which may be the same or different, each represents a alkyl group;R.sub.6 and R.sub.7, which may be the same or different, each represents an alkyl group or an aryl group;Q represents a pharmaceutically acceptable anion;l represents 1 or 2;m and n, which may be the same or different, each represents 0 or 1; and(B) a pharmaceutically acceptable carrier or diluent.
公开/授权文献
- US4325364A Training breathing apparatus 公开/授权日:1982-04-20