发明授权
- 专利标题: Use of recombinant B-cell differentiation factor for augmenting antibody production and stimulating bone marrow proliferation
- 专利标题(中): 使用重组B细胞分化因子增强抗体产生和刺激骨髓增殖
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申请号: US877731申请日: 1992-05-04
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公开(公告)号: US5362489A公开(公告)日: 1994-11-08
- 发明人: Tadamitsu Kishimoto , Toshio Hirano , Hiroshi Matsui , Yoshiyuki Takahara , Yukio Akiyama , Akira Okano
- 申请人: Tadamitsu Kishimoto , Toshio Hirano , Hiroshi Matsui , Yoshiyuki Takahara , Yukio Akiyama , Akira Okano
- 申请人地址: JPX Tokyo JPX Tondabayashi
- 专利权人: Ajinomoto Co., Inc.,Tadamitsu Kishimoto
- 当前专利权人: Ajinomoto Co., Inc.,Tadamitsu Kishimoto
- 当前专利权人地址: JPX Tokyo JPX Tondabayashi
- 优先权: JPX61-184858 19860806; JPX61-200433 19860827; JPX61-302699 19861218; JPX62-116332 19870513
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K14/54 ; C07K14/55 ; C12N1/21 ; C12N15/24 ; A61K37/02
摘要:
A purified human B-cell differentiation factor (BCDF) which does not have a natural signal peptide attached to the N-terminal thereof, DNA encoding the BCDF, transformed cells containing such DNA, a process for producing and obtaining the BCDF, compositions containing the BCDF and various therapeutic uses are disclosed.
公开/授权文献
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