A fuel injection and control system for a V-type, two cycle, crankcase compression, internal combustion engine. The fuel injection system includes fuel injectors positioned in the valley of the engine and which are supplied with fuel under pressure from a fuel tank through a line in which a fuel filter and fuel pump are positioned. The fuel pump and fuel filter are disposed at one end of the engine and the amount of pressure supplied to the fuel injectors is controlled by a pressure regulator that regulates pressure by bypassing excess fuel back to the fuel filter upstream of the filter element. A throttle control and throttle position sensor are disposed at the opposite end of the engine and exhaust control valves are provided outside of the valley of the "V" of the engine. The amount of air flow to the engine is sensed by a crankcase pressure sensor and an arrangement is incorporated for preventing damage to the crankcase pressure sensor by isolating it from negative pressure conditions which exist at times in the crankcase chamber.