发明授权
US5380850A (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of
leukotrienes
失效
(喹啉-2-基甲氧基)吲哚作为白三烯生物合成的抑制剂
- 专利标题: (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes
- 专利标题(中): (喹啉-2-基甲氧基)吲哚作为白三烯生物合成的抑制剂
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申请号: US168442申请日: 1993-12-16
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公开(公告)号: US5380850A公开(公告)日: 1995-01-10
- 发明人: Petpiboon Prasit , Rejean Fortin , John H. Hutchinson , Michel L. Belley , Serge Leger , Richard Frenette , John Gillard
- 申请人: Petpiboon Prasit , Rejean Fortin , John H. Hutchinson , Michel L. Belley , Serge Leger , Richard Frenette , John Gillard
- 申请人地址: CAX Kirkland
- 专利权人: Merck Frosst Canada, Inc.
- 当前专利权人: Merck Frosst Canada, Inc.
- 当前专利权人地址: CAX Kirkland
- 主分类号: A61K31/475
- IPC分类号: A61K31/475 ; C07D215/14 ; C07D401/12 ; C07C211/00 ; C07D215/12 ; C07D215/16
摘要:
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine. RELATED APPLICATION
公开/授权文献
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