发明授权
- 专利标题： 3-aryloxmethyl-cephalosporin derivatives, and their medical use
- 专利标题（中）： 3-芳氧基甲基头孢菌素衍生物及其医疗用途
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申请号： US880295申请日： 1992-05-05
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公开(公告)号： US5389626A公开(公告)日： 1995-02-14
- 发明人: Koichi Kojima , Kazuo Koyama , Shigeo Amemiya , Masayuki Iwata
- 申请人： Koichi Kojima , Kazuo Koyama , Shigeo Amemiya , Masayuki Iwata
- 申请人地址： JPX Tokyo
- 专利权人： Sankyo Company, Limited
- 当前专利权人： Sankyo Company, Limited
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX63-253253 19881007
- 主分类号： A61K31/545
- IPC分类号： A61K31/545 ; C07D20060101 ; C07D501/00 ; C07D501/16 ; C07D501/18 ; C07D501/26 ; C07D501/28 ; C07D501/30 ; C07D501/32 ; C07D501/34 ; C07D501/57
摘要：
Compounds of formula (I): ##STR1## in which: R.sup.1 is hydrogen or acyl; R.sup.2 is hydrogen or C.sub.1 -C.sub.4 alkoxy; and Ar is phenyl or substituted phenyl and pharmaceutically acceptable salts and esters thereof have valuable antibiotic activity, including against Methicillin-resistant strains of Staphylococcus. The invention also provides a process for preparing the compounds and methods and compositions using them.
公开/授权文献
- US5788069A CD holder with spring 公开/授权日：1998-08-04
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