发明授权
- 专利标题： Aminobenzoic acid derivatives useful for treating gastro-intestinal conditions
- 专利标题（中）： 用于治疗胃肠道病症的氨基苯甲酸衍生物
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申请号： US013080申请日： 1993-02-03
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公开(公告)号： US5389643A公开(公告)日： 1995-02-14
- 发明人: Shuhei Miyazawa , Shigeki Hibi , Hiroyuki Yoshimura , Takashi Mori , Yorihisa Hoshino , Mitsuo Nagai , Kouichi Kikuchi , Hisashi Shibata , Kazuo Hirota , Takashi Yamanaka , Isao Yamatsu , Masanori Mizuno
- 申请人： Shuhei Miyazawa , Shigeki Hibi , Hiroyuki Yoshimura , Takashi Mori , Yorihisa Hoshino , Mitsuo Nagai , Kouichi Kikuchi , Hisashi Shibata , Kazuo Hirota , Takashi Yamanaka , Isao Yamatsu , Masanori Mizuno
- 申请人地址： JPX Tokyo
- 专利权人： Eisai Co., Ltd.
- 当前专利权人： Eisai Co., Ltd.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX4-018959 19920204; JPX4-235533 19920903
- 主分类号： A61K31/46
- IPC分类号： A61K31/46 ; A61P1/00 ; A61P1/08 ; A61P25/20 ; A61P43/00 ; C07C229/60 ; C07C229/64 ; C07D451/04 ; C07D451/12 ; C07D451/06
摘要：
An aminobenzoic acid derivative represented by the following general formulas (I), (I-2) or (I-3), or a pharmacologically acceptable salt thereof, which exhibits a serotonin antagonism and an acetylcholine release accelerating activity at a well-balanced activity ratio and which is efficacious as a drug for patients with gastrointestinal unindentified complaints: ##STR1## wherein R.sup.1 represents a group such as an alkynyl or cyanoalkyl group; R.sup.2 represents a group such as an amino or acylamino group;R.sup.3 represents a halogen atom;X represents --O-- or --NH--; andA represents an oxygen or sulfur atom.
公开/授权文献
- US5958197A Catalysts for gas diffusion electrodes 公开/授权日：1999-09-28