An arrangement for retaining a tire on a vehicle wheel. The arrangement has a device for locking a tire against the wheel rim and pressing the tire beads against the rim flanges and rim seats. The device for locking the tire includes a plurality of clamping jaws disposed in spaced-apart relation to one another about the rim. Each jaw is rotatable about a clamping bolt. The rim of the wheel is provided, on its bottom, with fixing lugs. The jaws, when in an operative position, are applied against the fixing lugs to prevent the jaws from rotating about their clamping bolt.