发明授权
- 专利标题: Technetium-99m labeled somatostatin-derived peptides for imaging
- 专利标题(中): 锝-99m标记生长抑素衍生肽用于成像
-
申请号: US977628申请日: 1992-11-17
-
公开(公告)号: US5405597A公开(公告)日: 1995-04-11
- 发明人: Richard T. Dean , John Lister-James , Scott Buttram
- 申请人: Richard T. Dean , John Lister-James , Scott Buttram
- 申请人地址: NH Londonderry
- 专利权人: Diatech, Inc.
- 当前专利权人: Diatech, Inc.
- 当前专利权人地址: NH Londonderry
- 主分类号: A61K51/08
- IPC分类号: A61K51/08 ; A61K49/00
摘要:
The invention relates to radiolabeled imaging of a mammalian body. The invention in particular provides for reagents labeled with technetium-99m for such imaging. The invention specifically provides somatostatin, somatostatin derivatives, somatostatin analogues or peptides that bind to the somatostatin receptor and contain at least 2 cysteine residues that form a disulfide or wherein the disulfide is reduced to the sulfhydryl form that are labeled with technetium-99m and that can be targeted to specific sites within a mammalian body for imaging.
公开/授权文献
信息查询