发明授权
- 专利标题： Anti-octopus rhodopsin monoclonal antibody
- 专利标题（中）： 反章鱼视紫红质单克隆抗体
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申请号： US588783申请日： 1990-09-27
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公开(公告)号： US5414072A公开(公告)日： 1995-05-09
- 发明人: Tadashi Ishibashi , Hiroaki Kezuka , Saeko Yoshino , Norio Shimizu , Motoyuki Tsuda , Shuji Imazeki
- 申请人： Tadashi Ishibashi , Hiroaki Kezuka , Saeko Yoshino , Norio Shimizu , Motoyuki Tsuda , Shuji Imazeki
- 申请人地址： JPX Tokyo
- 专利权人： Hitachi, Ltd.
- 当前专利权人： Hitachi, Ltd.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX1-249138 19890927; JPX2-45410 19900228; JPX2-138209 19900530
- 主分类号： C07K16/18
- IPC分类号： C07K16/18 ; C12P21/08 ; C12N5/20 ; C12N15/02
摘要：
The invention relates to a monoclonal antibody which binds to octopus rhodopsin and octopus metarhodopsin wherein said monoclonal antibody binds with higher affinity to metarhodopsin than to rhodopsin and does not inhibit rhodopsin-metarhodopsin interconversion upon exposure to blue or red light. The monoclonal antibody binds to a peptide having the sequence Val-Ile-Gly-Arg-Pro-Met-Ala-Ala-Ser-Lys-Lys-Met-Ser. The photochemical reaction of rhodopsin thin layers may be detected using the anti-rhodopsin monoclonal antibodies of the invention.
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