发明授权
US5434164A Carbostyril derivatives and salts thereof and pharmaceutical
compositions for inhibiting adhesion of thrombocytes
失效
卡波他特尔衍生物及其盐和用于抑制凝血细胞粘附的药物组合物
- 专利标题: Carbostyril derivatives and salts thereof and pharmaceutical compositions for inhibiting adhesion of thrombocytes
- 专利标题(中): 卡波他特尔衍生物及其盐和用于抑制凝血细胞粘附的药物组合物
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申请号: US958489申请日: 1992-10-08
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公开(公告)号: US5434164A公开(公告)日: 1995-07-18
- 发明人: Takao Nishi , Tetsuyuki Uno , Yasuo Koga , Gil-Namg Chu
- 申请人: Takao Nishi , Tetsuyuki Uno , Yasuo Koga , Gil-Namg Chu
- 申请人地址: JPX
- 专利权人: Otsuka Pharmaceutical Co. Ltd.
- 当前专利权人: Otsuka Pharmaceutical Co. Ltd.
- 当前专利权人地址: JPX
- 优先权: JPX61-76089 19860402; JPX62-43457 19870225; JPX62-60770 19870316
- 主分类号: A61K31/47
- IPC分类号: A61K31/47 ; C07D401/12 ; C07D401/14 ; C07D405/12 ; C07D417/12 ; C07D403/02
摘要:
Carbostyril derivatives and salts thereof represented by the general formula (1a), including some known compounds, possess activities for inhibiting adhesion of thrombocytes. ##STR1## Z, A, X, R, R.sup.1 and R.sup.2 are defined in the specification. Some carbostyril derivatives having chemical structural formulas similar to those of carbostyril derivatives and salts thereof represented by the general formula (1a) have been known in prior art references, however the above-mentioned pharmacological activities have not been known to the present date.
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