发明授权
- 专利标题: Method of treating certain tumors using illudin analogs
- 专利标题(中): 使用illudin类似物治疗某些肿瘤的方法
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申请号: US15179申请日: 1993-02-09
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公开(公告)号: US5439936A公开(公告)日: 1995-08-08
- 发明人: Michael J. Kelner , Trevor C. McMorris , Raymond Taetle
- 申请人: Michael J. Kelner , Trevor C. McMorris , Raymond Taetle
- 申请人地址: CA Oakland
- 专利权人: The Regents of the University of California
- 当前专利权人: The Regents of the University of California
- 当前专利权人地址: CA Oakland
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61K31/12 ; A61K31/122 ; A61K31/215 ; A61K31/22 ; A61K31/27 ; A61P35/00 ; A61P35/02 ; C07C45/45 ; C07C45/46 ; C07C45/65 ; C07C45/67 ; C07C49/67 ; C07C49/683 ; C07C49/737 ; C07C49/747 ; C07C49/753 ; C07C49/755 ; C07C69/007 ; C07C69/16 ; C07C69/63 ; C07C69/732 ; C07C69/76 ; C07C271/10 ; C07C271/12
摘要:
A therapeutic method is provided to inhibit tumor cell growth in a subject in need of said therapy is provided, comprising parenterally administering a therapeutic amount of a compound in a pharmaceutically acceptable carrier, wherein said compound has the structure: ##STR1## wherein R is selected from the group consisting of: ##STR2## and wherein said tumor cell is sensitive to inhibition by said compound and is selected from the group consisting of a myeloid leukemia cell, a T-cell leukemia cell, a lung carcinoma cell, an ovarian carcinoma cell, and a breast carcinoma cell.
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