Invention Grant
- Patent Title: Vasoactive vasotocin derivatives
- Patent Title (中): 血管活性血管生成衍生物
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Application No.: US923895Application Date: 1992-09-23
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Publication No.: US5459236APublication Date: 1995-10-17
- Inventor: Carl-Johan Aurell , Per Melin , Anders Nilsson , Jerzy Trojnar
- Applicant: Carl-Johan Aurell , Per Melin , Anders Nilsson , Jerzy Trojnar
- Applicant Address: SEX Malmoe
- Assignee: Ferring AB
- Current Assignee: Ferring AB
- Current Assignee Address: SEX Malmoe
- Priority: SEX9000691 19900227
- Main IPC: A61K38/11
- IPC: A61K38/11 ; A61K20060101 ; A61K31/00 ; A61K38/00 ; A61K38/12 ; A61P5/28 ; A61P9/02 ; C07K20060101 ; C07K7/00 ; C07K7/02 ; C07K7/06 ; C07K7/16 ; C07K7/52
Abstract:
The present invention relates to new vasotocin derivatives with prolonged activity compared to previous vasotocin derivatives. In particular, the vasotocin derivatives of the present invention are of the formula (I) ##STR1## wherein Hmp is a 2-hydroxy-3-mercaptopropionic acid residue, ##STR2## Z is Phe or Tyr, Y is Hgn or Hci, X is a residue of the formula ##STR3## wherein Q is H, alanyl or L-2-aminobutyryl and n is 1, 2 or 3. The present invention also relates to pharmaceutical compositions containing these vasotocin derivatives.
Public/Granted literature
- US5963516A Tracking control apparatus of optical disc apparatus and method of same Public/Granted day:1999-10-05
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