This invention relates to a device, a system and a method for locating a printing screen at a selected starting position for printing operations and for resetting the screen to the starting position for its adjustment relative to an article. The device includes first and second centering plates disposed in overlapping relationship to one another. The plates are mounted to respective first and second moveable screen support members. At least one micro-adjuster is associated with each support member for effecting precise adjustment of the respective centering plates and, hence, the screen. A first micro-adjuster effects longitudinal movement of the first member and a second effects movement of the second member laterally. Thereby, planar movement of the screen and the associated centering plates is effected. The device also has an arm with an aperture for receiving and engaging a screen centering member. The member passes through the aperture and into engagement with a corresponding receptacle in the screen. Micro-adjusters associated with the support members are then manipulated so as to place the screen in precise registration with the article. A hole is made in each of the first and second plates at a location where the plates overlap. Upon passing a pin through the holes, the starting or reset position for screen adjustment is defined.