发明授权
- 专利标题: Alcohols
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申请号: US439612申请日: 1995-05-12
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公开(公告)号: US5488115A公开(公告)日: 1996-01-30
- 发明人: Kevin E. B. Parkes , Sally Redshaw , Gareth J. Thomas
- 申请人: Kevin E. B. Parkes , Sally Redshaw , Gareth J. Thomas
- 申请人地址: NJ Nutley
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: NJ Nutley
- 优先权: GBX8927915 19891211
- 主分类号: C07D209/48
- IPC分类号: C07D209/48 ; C07C247/04 ; C07C247/06 ; C07C247/10 ; C07D217/26 ; C07D303/36 ; C07D327/10 ; C07D333/36 ; C07D401/06 ; C07D405/06
摘要:
Novel alcohols of the formula ##STR1## wherein R.sup.a is azido or phthalimido, R.sup.4 is alkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl, R.sup.7 and R.sup.8 together are a trimethylene or tetramethylene group which is optionally substituted by hydroxy, alkoxycarbonylamino or acylamino or in which one --CH.sub.2 -- group is replaced by --NH--, --N(alkoxycarbonyl)--, --N(acyl)-- or --S-- or which carries a fused cycloalkane, aromatic or heteroaromatic ring, and R.sup.9 is alkoxycarbonyl, monoalkylcarbamoyl, monoaralkylcarbamoyl, monoarylcarbamoyl or a group of the formula ##STR2## in which R.sup.10 and R.sup.11 each is alkyl, are described along with a process for their manufacture. These alcohols are useful as intermediates, for example in the manufacture of amino acid derivatives having antiviral activity.
公开/授权文献
- US5020818A All-terrain wheelchair 公开/授权日:1991-06-04