发明授权
- 专利标题： Fixed tissue medical devices comprising albumin-binding dyes
- 专利标题（中）： 包含白蛋白结合染料的固定组织医疗装置
-
申请号： US044846申请日： 1993-04-08
-
公开(公告)号： US5509932A公开(公告)日： 1996-04-23
- 发明人: James R. Keogh , David A. Pearson , John W. Eaton
- 申请人： James R. Keogh , David A. Pearson , John W. Eaton
- 专利权人： Keogh; James R.,Pearson; David A.,Eaton; John W.
- 当前专利权人： Keogh; James R.,Pearson; David A.,Eaton; John W.
- 主分类号： A61F2/24
- IPC分类号： A61F2/24 ; A61L27/28 ; A61L27/34 ; A61F2/02
摘要：
An implantable medical device is provided which comprises a fixed tissue incorporating an amount of an albumin-binding dye effective to form a coating of endogenous albumin on said device when the device is in contact with a physiological fluid containing albumin. These albumin-binding dyes have been found to significantly reduce calcification when incorporated in tissue heart valves. A method of increasing the albumin-binding ability of an implantable medical device is also provided.