发明授权
- 专利标题: Compounds and use thereof
- 专利标题(中): 化合物及其用途
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申请号: US312638申请日: 1994-09-27
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公开(公告)号: US5530138A公开(公告)日: 1996-06-25
- 发明人: Yutaka Baba , Tomoo Suzuki , Tsunemasa Suzuki , Kiyotaka Hirooka , Masayasu Kurono , Kiichi Sawai
- 申请人: Yutaka Baba , Tomoo Suzuki , Tsunemasa Suzuki , Kiyotaka Hirooka , Masayasu Kurono , Kiichi Sawai
- 申请人地址: JPX Aichi-ken
- 专利权人: Sanwa Kagaku Kenkyusho Co., Ltd.
- 当前专利权人: Sanwa Kagaku Kenkyusho Co., Ltd.
- 当前专利权人地址: JPX Aichi-ken
- 优先权: JPX5-250343 19931006; JPX6-193116 19940817
- 主分类号: A61K31/00
- IPC分类号: A61K31/00 ; A61K31/40 ; A61K31/407 ; A61P25/00 ; A61P25/02 ; A61P25/18 ; A61P25/28 ; C07D487/04 ; C07D451/02
摘要:
There is disclosed a compound shown by a formula of ##STR1## wherein R.sub.1 is a hydrogen atom alkyl group having 1-4 carbon atoms or acyl group having 1-4 carbon atoms: R.sub.2 and R.sub.3 are a hydrogen atom, alkyl group having 1-4 carbon atoms, phenyl radical, halogen atom, cyano radical, acyl group having 1-4 carbon atoms, nitro radical, alkoxy group having 1 or 2 carbon atoms, or substituted or non-substituted amino group, respectively; n is an integer of 1-3; and dotted line means a possible ring, and a salt thereof. The compound and salt bind with muscarinic receptor in brain to develop a powerful actuation thereof and thus those can be used as an effective ingredient for preventing and curing senile dementias, and more particularly Alzheimer's disease.
公开/授权文献
- US4944652A Process and device for the control of turbo compressors 公开/授权日:1990-07-31