发明授权
- 专利标题: Acrylacetamides
- 专利标题(中): 丙烯酰胺
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申请号: US453811申请日: 1995-05-30
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公开(公告)号: US5532266A公开(公告)日: 1996-07-02
- 发明人: Rudolf Gottschlich , Karl-August Ackermann , Helmut Prucher , Christoph Seyfried , Hartmut Greiner , Gerd Bartoszyk , Frank Mauler , Manfred Stohrer , Andrew Barber
- 申请人: Rudolf Gottschlich , Karl-August Ackermann , Helmut Prucher , Christoph Seyfried , Hartmut Greiner , Gerd Bartoszyk , Frank Mauler , Manfred Stohrer , Andrew Barber
- 申请人地址: DEX Darmstadt
- 专利权人: Merck Patent Gesellschaft mit beschrankter Haftung
- 当前专利权人: Merck Patent Gesellschaft mit beschrankter Haftung
- 当前专利权人地址: DEX Darmstadt
- 优先权: DEX4215213.5 19920509
- 主分类号: A61K31/435
- IPC分类号: A61K31/435 ; A61K31/165 ; A61K31/17 ; A61K31/35 ; A61K31/40 ; A61K31/4025 ; A61K31/47 ; A61K31/472 ; A61K31/495 ; A61K31/535 ; A61P7/10 ; A61P11/08 ; A61P11/14 ; A61P25/04 ; A61P25/08 ; A61P25/28 ; A61P29/00 ; A61P43/00 ; C07C233/00 ; C07C233/05 ; C07C233/08 ; C07D207/08 ; C07D207/09 ; C07D207/12 ; C07D215/00 ; C07D217/06 ; C07D217/14 ; C07D295/12 ; C07D295/135 ; C07D311/84 ; C07D401/06 ; C07D403/06 ; C07D405/06 ; C07D405/12 ; C07D409/06 ; C07D413/06 ; C07D207/36 ; C07D207/325
摘要:
Novel arylacetamides of the formula I ##STR1## in which Q is R.sup.4 --CH(CH.sub.2 Z)--NA--, ##STR2## R.sup.1 is Ar, cycloalkyl with 3-7 C atoms or C.sub.4 -C.sub.8 -cycloalkyl-C.sub.1 -C.sub.7 -alkyl,R.sup.2 is Ar,R.sup.3 is H, OH, OA or A,R.sup.4 is A or phenyl which can optionally be substituted once or twice by F, Cl, Br, I, OH, OA, CF.sub.3, NO.sub.2, NH.sub.2, NHA, NHCOA, NHSO.sub.2 A or NA.sub.2,R.sup.5 and R.sup.6 are each, independently of one another, H, F, Cl, Br, I, OH, OA, CF.sub.3, NH.sub.2, NHA, NA.sub.2, NHCOA, NHCONH.sub.2, NO.sub.2 or taken together are methylenedioxy,A is alkyl with 1-7 C atoms, and physiologically acceptable salts thereof.
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