- 专利标题： Receptor-type phosphotyrosine phosphatase-alpha
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申请号： US15985申请日： 1993-02-10
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公开(公告)号： US5538886A公开(公告)日： 1996-07-23
- 发明人: Joseph Schlessinger , Jan M. Sap
- 申请人： Joseph Schlessinger , Jan M. Sap
- 申请人地址： NY New York
- 专利权人： New York University
- 当前专利权人： New York University
- 当前专利权人地址： NY New York
- 主分类号： C07K14/705
- IPC分类号： C07K14/705 ; C12N9/16 ; C12N15/55 ; C12N1/21 ; C12N5/10 ; C12N15/63
摘要：
A novel receptor-type protein tyrosine phosphatase (RPTP) protein or glycoprotein and the DNA coding therefor is expressed in a wide variety of mammalian tissues. Included in this family of proteins are human RPTP.alpha., human RPTP.beta. and human RPTP.gamma.. The RPTP protein or glycoprotein may be produced by recombinant means. Antibodies to the proteins, methods for measuring the quantity of the proteins, methods for screening compounds, such as drugs, which can bind to the proteins and inhibit or stimulate their activity, are provided.