发明授权
US5538984A Methods of using piperidyl-benzisoxazole and benisothiazole derivatives
as cholinesterase inhibitors
失效
使用哌啶基 - 苯并异恶唑和苯并异噻唑衍生物作为胆碱酯酶抑制剂的方法
- 专利标题: Methods of using piperidyl-benzisoxazole and benisothiazole derivatives as cholinesterase inhibitors
- 专利标题(中): 使用哌啶基 - 苯并异恶唑和苯并异噻唑衍生物作为胆碱酯酶抑制剂的方法
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申请号: US445814申请日: 1995-05-22
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公开(公告)号: US5538984A公开(公告)日: 1996-07-23
- 发明人: Anabella Villalobos , Arthur A. Nagel , Yuhpyng L. Chen
- 申请人: Anabella Villalobos , Arthur A. Nagel , Yuhpyng L. Chen
- 申请人地址: NY New York
- 专利权人: Pfizer Inc.
- 当前专利权人: Pfizer Inc.
- 当前专利权人地址: NY New York
- 主分类号: A61K31/454
- IPC分类号: A61K31/454 ; C07D211/32 ; C07D261/20 ; C07D401/06 ; C07D413/06 ; C07D413/12 ; C07D413/14 ; C07D417/06 ; C07D498/04 ; A61K31/445 ; A61K31/495 ; C07D401/12
摘要:
Disclosed herein are compounds of the formula ##STR1## wherein R.sup.1 R.sup.2, R.sup.7, R.sup.8, X, Y, M and L are defined as below The compounds of formula I are cholinesterase inhibitors and are useful in enhancing memory in patients suffering from dementia and Alzheimer's disease.