发明授权
US5545533A Monoclonal antibodies against c-kit and method of detecting a malignancy
using c-kit specific antibodies
失效
针对c-kit的单克隆抗体以及使用c-kit特异性抗体检测恶性肿瘤的方法
- 专利标题： Monoclonal antibodies against c-kit and method of detecting a malignancy using c-kit specific antibodies
- 专利标题（中）： 针对c-kit的单克隆抗体以及使用c-kit特异性抗体检测恶性肿瘤的方法
-
申请号： US469778申请日： 1995-06-06
-
公开(公告)号： US5545533A公开(公告)日： 1996-08-13
- 发明人: Ilse Bartke , Gunter Kostka , Kurt Naujoks , Axel Ullrich
- 申请人： Ilse Bartke , Gunter Kostka , Kurt Naujoks , Axel Ullrich
- 申请人地址： DEX Mannheim
- 专利权人： Boehringer Mannheim GmbH
- 当前专利权人： Boehringer Mannheim GmbH
- 当前专利权人地址： DEX Mannheim
- 优先权： DEX4117090.3 19910525; DEX4205148.7 19920220
- 主分类号： C07K16/32
- IPC分类号： C07K16/32 ; G01N33/53 ; C12N5/20
摘要：
The invention concerns monoclonal antibodies against the human c-kit receptor which are obtainable from the cell lines DSM ACC 2007, DSM ACC 2008 and DSM ACC 2009 or are capable of binding to the c-kit receptor in an equivalent manner to the antibodies produced by the cell lines DSM ACC 2007, DSM ACC 2008 or DSM ACC 2009. The present invention also concerns a method for testing the malignancy of tumours of haematopoietic cells, of seminomas or small-celled lung carcinoma in which a tissue sample is incubated with at least one monoclonal antibody against the c-kit receptor according to the present invention and subsequently bound antibodies are detected by means of known methods.
公开/授权文献
- US5100663A Tyr-Gly compositions useful in increasing immune response 公开/授权日：1992-03-31
信息查询
