发明授权
US5547983A Aromatic and polycyclic compounds and their use in human or veterinary
medicine and in cosmetics
失效
芳香族和多环化合物及其在人类或兽医学和化妆品中的应用
- 专利标题: Aromatic and polycyclic compounds and their use in human or veterinary medicine and in cosmetics
- 专利标题(中): 芳香族和多环化合物及其在人类或兽医学和化妆品中的应用
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申请号: US140079申请日: 1994-08-22
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公开(公告)号: US5547983A公开(公告)日: 1996-08-20
- 发明人: Bruno Charpentier
- 申请人: Bruno Charpentier
- 申请人地址: FRX Valbonne
- 专利权人: Centre International de Recherches Dermatologiques Galderma (CIRD Galderma)
- 当前专利权人: Centre International de Recherches Dermatologiques Galderma (CIRD Galderma)
- 当前专利权人地址: FRX Valbonne
- 优先权: FRX9105394 19910502
- 主分类号: C07C49/84
- IPC分类号: C07C49/84 ; C07C63/49 ; C07C65/17 ; C07C65/26 ; C07C69/00 ; C07C69/007 ; C07C69/88 ; C07C217/18 ; C07C233/65 ; C07C309/65 ; C07D295/192 ; C07D303/40 ; C07D317/60 ; C07C63/44
摘要:
Aromatic bicyclic compounds of formula (I) ##STR1## where R.sub.1 is specifically --H, CH.sub.3, --CH.sub.2 OH, --OH, --CHO, --CONH.sub.2, --COOH, --COOalkyl, --SH, S-alkyl, etc. . . . ; R.sub.2 is H; R.sub.3 is H, aryl, aralkyl or lower alkyl optionally substituted by a hydroxyl, a lower alkoxy or a --CO--R.sub.12, R.sub.12 being specifically H, lower alkyl, hydroxyl, lower alkoxy, or R.sub.2 and R.sub.3 together form a naphthalene ring with the benzene ring; R.sub.4 is a linear branched or unbranched alkyl having 1 to 15 carbon atoms or a cycloaliphatic radical; R.sub.5 represents specifically --(CH.sub.2).sub.n --R.sub.13, --CH.dbd.CH--(CH.sub.2).sub.n --R.sub.13, n being 0 or 1 to 6, R.sub.13 representing --COR.sub.15, monohydroxyalkyl, polyhydroxyalkyl, epoxy lower alkyl or --O--CO--R.sub.16, R.sub.15 representing specifically --OH, --Oalkyl, --Oaryl, R.sub.16 being specifically H, lower alkyl, aryl, or aralkyl; R.sub.6 and R.sub.7 are H, a halogen, lower alkyl or --OR.sub.16 ; and also the salts of the compounds of formula (I) in which R.sub.1 represents a carboxylic acid grouping; and the chiral analogues of the said compounds of formula (I).
公开/授权文献
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