The invention relates to a bicycle lock which passes through the spokes of a bicycle wheel to prevent the bicycle from being ridden. A preferred embodiment of the invention includes a locking bracket positioned on a first frame member at one side of the wheel and a receiving bracket positioned on a second frame member on an opposite side of the wheel from the locking bracket. A lock pin is provided which extends from one bracket to the other through the spokes of the bicycle wheel. The lock pin is positioned in a through hole of the locking bracket and in a blind hole in the receiving bracket. The locking bracket has a locking mechanism for locking the lock pin in place.