发明授权
US5567724A Alkaline and acid phosphatase inhibitors in treatment of neurological
disorders
失效
碱性和酸性磷酸酶抑制剂治疗神经系统疾病
- 专利标题： Alkaline and acid phosphatase inhibitors in treatment of neurological disorders
- 专利标题（中）： 碱性和酸性磷酸酶抑制剂治疗神经系统疾病
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申请号： US252109申请日： 1994-06-01
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公开(公告)号： US5567724A公开(公告)日： 1996-10-22
- 发明人: Judith A. Kelleher , David D. Eveleth
- 申请人： Judith A. Kelleher , David D. Eveleth
- 申请人地址： CA Irvine
- 专利权人： Cortex Pharmaceuticals, Inc.
- 当前专利权人： Cortex Pharmaceuticals, Inc.
- 当前专利权人地址： CA Irvine
- 主分类号： C07D513/04
- IPC分类号： C07D513/04 ; A61K31/00 ; A61K31/19 ; A61K31/305 ; A61K31/425 ; A61K33/00 ; A61K33/16 ; A61K45/00 ; A61P25/28 ; A61P43/00 ; A61K31/38
摘要：
The present invention provides a method of inhibiting .beta.-amyloid toxicity in brain cells. The method includes administering to the cells an amount of an alkaline phosphatase inhibitor which is pharmacologically effective to reduce degeneration in the cells. Methods of treatment of peripheral neuropathy are also provided using acid or alkaline phosphatase inhibitors.