发明授权
US5571679A Anti-EDA monoclonal antibody and a method for diagnosis of disease
associated with the EDA region of fibronectin
失效
抗EDA单克隆抗体和与纤连蛋白EDA区相关疾病的诊断方法
- 专利标题： Anti-EDA monoclonal antibody and a method for diagnosis of disease associated with the EDA region of fibronectin
- 专利标题（中）： 抗EDA单克隆抗体和与纤连蛋白EDA区相关疾病的诊断方法
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申请号： US119231申请日： 1993-09-22
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公开(公告)号： US5571679A公开(公告)日： 1996-11-05
- 发明人: Kiyotoshi Sekiguchi , Kaneji Asakawa , Eiji Sakashita , Kazuo Hino , Sadahito Shin , Tetsuya Tachikawa , Hisanobu Hirano
- 申请人： Kiyotoshi Sekiguchi , Kaneji Asakawa , Eiji Sakashita , Kazuo Hino , Sadahito Shin , Tetsuya Tachikawa , Hisanobu Hirano
- 申请人地址： JPX Tokushima
- 专利权人： Otsuka Pharmaceutical Factory, Inc.
- 当前专利权人： Otsuka Pharmaceutical Factory, Inc.
- 当前专利权人地址： JPX Tokushima
- 优先权： JPX3-061524 19910326; JPX3-157966 19910628; JPX3-286668 19911031
- 主分类号： C07K14/78
- IPC分类号： C07K14/78 ; C07K16/18 ; C12N5/20 ; C12P21/08 ; G01N33/53
摘要：
The invention provides an anti-EDA monoclonal antibody which recognizes an amino acid sequence portion in the EDA region of fibronectin (FN). The antibody of the invention has specific reactivity against EDA, in particular EDA-FN. By utilizing it, a simple and easy, high-sensitivity and high-precision immunoassay method for EDA-FN as well as a screening or diagnostic technique for EDA-FN-associated inflammatory and other diseases can be established.
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