发明授权
US5582862A Antibodies that bind to .alpha.2-antiplasmin crosslinked to fibrin which
do not inhibit plasma .alpha.2-antiplasmin
失效
结合到不抑制血浆α2-抗血纤维蛋白的纤维蛋白交联的α2-抗血纤维蛋白的抗体
- 专利标题： Antibodies that bind to .alpha.2-antiplasmin crosslinked to fibrin which do not inhibit plasma .alpha.2-antiplasmin
- 专利标题（中）： 结合到不抑制血浆α2-抗血纤维蛋白的纤维蛋白交联的α2-抗血纤维蛋白的抗体
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申请号： US980520申请日： 1992-12-01
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公开(公告)号： US5582862A公开(公告)日： 1996-12-10
- 发明人: Guy L. Reed , Edgar Haber , Gary R. Matsueda
- 申请人： Guy L. Reed , Edgar Haber , Gary R. Matsueda
- 申请人地址： MA Boston
- 专利权人： General Hospital Corporation
- 当前专利权人： General Hospital Corporation
- 当前专利权人地址： MA Boston
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K38/49 ; A61K39/395 ; A61K45/06 ; C07K16/38 ; C07K16/40 ; C12P21/08 ; A61K38/48
摘要：
The present invention relates to a treatment for myocardial infarction and blood clots within a patient, and more specifically to a therapy which enhances clot lysis comprising administering to a patient an antibody directed to .alpha.2-antiplasmin crosslinked to fibrin (.alpha.2AP-Fx) which does not inhibit plasma .alpha.2-antiplasmin (.alpha.2AP). The invention also relates to a treatment for enhancing clot lysis comprising administering an antibody directed toward .alpha.2-antiplasmin crosslinked to fibrin which does not inhibit plasma .alpha.2AP together with a thrombolytic agent.
公开/授权文献
- US6098568A Mixed frequency CVD apparatus 公开/授权日：2000-08-08
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