发明授权
- 专利标题： Crystalline amifostine compositions
- 专利标题（中）： 结晶氨磷汀组合物
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申请号： US389386申请日： 1995-02-16
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公开(公告)号： US5591731A公开(公告)日： 1997-01-07
- 发明人: Paul E. Kennedy , Roger A. Rajewski , John M. Baldoni
- 申请人： Paul E. Kennedy , Roger A. Rajewski , John M. Baldoni
- 申请人地址： PA West Conshohocken
- 专利权人： U.S. Bioscience, Inc.
- 当前专利权人： U.S. Bioscience, Inc.
- 当前专利权人地址： PA West Conshohocken
- 主分类号： A61K31/67
- IPC分类号： A61K31/67 ; A61K9/00 ; A61K9/19 ; A61K31/66 ; A61K31/661 ; A61K47/02 ; A61K47/18 ; A61K47/26 ; A61P39/00 ; A61P43/00 ; C07F9/165
摘要：
The present invention relates to a sterile, stable vacuum dried crystalline amifostine composition and, optionally, pharmaceutically acceptable excipient(s). Typically, the crystalline compositions of the present invention exhibit enhanced stability at temperatures ranging from about 4.degree. C. to about ambient temperature for a period of at least 2 years relative to existing solid vacuum dried amorphous amifostine preparations. The reconstituted compositions of the present invention are suitable for administration to humans as a radio- or chemoprotecting agent.
公开/授权文献
- US5167010A Expert advice display processing system 公开/授权日：1992-11-24
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