发明授权
US5597820A 1, 4-benzoxazine derivative and pharmaceutical compositions containing
the same
失效
1,4-苯并恶嗪衍生物和含有它们的药物组合物
- 专利标题： 1, 4-benzoxazine derivative and pharmaceutical compositions containing the same
- 专利标题（中）： 1,4-苯并恶嗪衍生物和含有它们的药物组合物
-
申请号： US577348申请日： 1995-12-22
-
公开(公告)号： US5597820A公开(公告)日： 1997-01-28
- 发明人: Manabu Hori , Ikuo Watanabe , Hiroshi Ohtaka , Kengo Harada , Joji Maruo , Tominori Morita , Takeshi Yamamoto , Hisayoshi Tsutsui
- 申请人： Manabu Hori , Ikuo Watanabe , Hiroshi Ohtaka , Kengo Harada , Joji Maruo , Tominori Morita , Takeshi Yamamoto , Hisayoshi Tsutsui
- 申请人地址： JPX Toyko-to
- 专利权人： Kanebo, Ltd.
- 当前专利权人： Kanebo, Ltd.
- 当前专利权人地址： JPX Toyko-to
- 优先权： JPX6-340044 19941227; JPX7-195939 19950707
- 主分类号： C07D265/36
- IPC分类号： C07D265/36 ; A61K31/535
摘要：
A 1,4-benzoxazine derivative of the following formula (I): ##STR1## or a pharmaceutically acceptable salt thereof is disclosed. The compound of the present invention is useful as a medicament for preventing or treating disorders induced by intracellular acidosis during myocardial ischemia, such as cardiac dysfunction, myocardial necrosis, arrhythmia, reperfusion injury, and the like, which are observed in ischemic heart diseases (e.g. myocardial infarction, angina pectoris, etc.).
公开/授权文献
信息查询
