发明授权
US5614643A Process for the enzymatic production of isomerically pure isosorbide-2
and 5-monoesters as well as their conversion into isosorbide-2- and
5-nitrate
失效
用于酶促生产异构纯的异山梨醇2和5-单酯的方法以及它们转化为异山梨醇-2-和5-硝酸盐
- 专利标题: Process for the enzymatic production of isomerically pure isosorbide-2 and 5-monoesters as well as their conversion into isosorbide-2- and 5-nitrate
- 专利标题(中): 用于酶促生产异构纯的异山梨醇2和5-单酯的方法以及它们转化为异山梨醇-2-和5-硝酸盐
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申请号: US481915申请日: 1995-06-07
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公开(公告)号: US5614643A公开(公告)日: 1997-03-25
- 发明人: Manfred Schneider , Robert Seemayer
- 申请人: Manfred Schneider , Robert Seemayer
- 申请人地址: DEX Mannheim
- 专利权人: Boehringer Mannheim GmbH
- 当前专利权人: Boehringer Mannheim GmbH
- 当前专利权人地址: DEX Mannheim
- 优先权: DEX4129093.3 19910902
- 主分类号: C07D493/04
- IPC分类号: C07D493/04 ; C12P17/18 ; C07D493/00
摘要:
Process for the enzymatic production of isomerically pure compounds having the general formulae I and II ##STR1## in which the substituents R have the meanings stated in the claims, as well as their use for the production of isomerically pure isosorbide-2-nitrate having the formula V and isosorbide-5-nitrate having the formula VI, ##STR2## which are both important as therapeutic agents for coronary diseases.
公开/授权文献
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