发明授权
- 专利标题: Prosthetic articular cartilage
- 专利标题(中): 假肢关节软骨
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申请号: US232743申请日: 1994-04-25
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公开(公告)号: US5624463A公开(公告)日: 1997-04-29
- 发明人: Kevin R. Stone , Shu-Tung Li
- 申请人: Kevin R. Stone , Shu-Tung Li
- 申请人地址: CA Redwood City
- 专利权人: ReGen Biologics, Inc.
- 当前专利权人: ReGen Biologics, Inc.
- 当前专利权人地址: CA Redwood City
- 主分类号: A61L27/00
- IPC分类号: A61L27/00 ; A61F2/00 ; A61F2/02 ; A61F2/28 ; A61F2/30 ; A61F2/38 ; A61F2/42 ; A61F2/44 ; A61L27/20 ; A61L27/22 ; A61L27/24 ; A61L27/26 ; A61L27/46 ; A61L27/48 ; A61L27/54 ; A61L27/56 ; A61L27/58 ; A61F2/50
摘要:
A prosthetic, resorbable articular cartilage and methods of its fabrication and insertion are disclosed. The prosthetic articular cartilage, when implanted in a humanoid joint, acts as a resorbable scaffold for ingrowth of native articular chondrocytes and supports natural articulating joint forces. The prosthetic articular cartilage is a dry, porous, volume matrix of biocompatible and bioresorbable fibers. These fibers include a natural polymer or analogs thereof, at least a portion of which may be crosslinked. The matrix is adapted to have an in vivo outer surface contour substantially the same as that of natural articular cartilage in an articulating joint, and has a pore size in the approximate range of about 100 microns to about 400 microns.
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