A non-azeotropic refrigerant composition which can be used in refrigerators originally designed to use a Freon refrigerant without the need of changing the specifications thereof, and which is harmless to men and environment. The refrigerant composition consists essentially of 70 parts by weight of butane (C.sub.4 H.sub.10), 25 parts by weight of ethyl ether (C.sub.2 H.sub.5).sub.2 O, and 5 parts by weight of dimethyl polysiloxane (silicone oil). The refrigerant composition exhibits approximately the same characteristics as those of R-12 and R-134a. Ethylene glycol and propylene glycol may be added thereto.