Invention Grant
- Patent Title: Anti-tumor platinum complexes, their preparation and their therapeutic use
- Patent Title (中): 抗肿瘤铂复合物，其制备及其治疗用途
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Application No.: US472128Application Date: 1995-06-07
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Publication No.: US5633243APublication Date: 1997-05-27
- Inventor: Yukio Sugimura , Tomoyuki Shibata , Yukiko Kameyama , Kimio Iino , Shigeki Muramatsu , Tomowo Kobayashi , Toshihiko Hashimoto
- Applicant: Yukio Sugimura , Tomoyuki Shibata , Yukiko Kameyama , Kimio Iino , Shigeki Muramatsu , Tomowo Kobayashi , Toshihiko Hashimoto
- Applicant Address: JPX Tokyo
- Assignee: Sankyo Company, Limited
- Current Assignee: Sankyo Company, Limited
- Current Assignee Address: JPX Tokyo
- Priority: JPX62-112181 19870508; JPX62-114500 19870513
- Main IPC: C07F15/00
- IPC: C07F15/00 ; A61K31/555 ; C07D205/08 ; C07D207/277
Abstract:
Compounds of formula (I): ##STR1## in which: A and B are separately monoamines or together diamines; and Z is a group of formula (II) or (III): ##STR2## (in which R.sup.1, R.sup.2 and R.sup.7 are various organic groups, n is 0, 1 or 2 and X is a direct carbon-carbon bond or lower alkylene) show valuable anti-tumor activity and may be prepared by reacting an amine-platinum complex with a compound providing the group represented by Z.
Public/Granted literature
- US5242800A Receptor for pathogenic fungi Public/Granted day:1993-09-07
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