A harmonica holder that has multiple sides, with clips that hold a harmonica securely to each side of the holder, so that a musician may play a harmonica without use of his hands. The musician can quickly change harmonicas by rotating the harmonica holder by hand or by use of a motor that can be operated by a footswitch. The harmonica holder has a microphone inside, for amplifying the sound of the harmonica being played, this microphone is controlled by a volume control/on-off switch. Sympathetically vibrating strings assist in the resonance of the harmonicas, these strings are secured inside the harmonica holder, and can be adjusted from the outside of the harmonica holder with a friction tuning peg. The harmonica holder has a standard bracket that enables it to be mounted on a standard microphone stand.